Neutrophils Higher In Pregnancy

Neutrophils Higher In Pregnancy

Neutrophils are a type of white blood cell that play a vital role in defending against invading microorganisms. So what does it mean if neutrophils are elevated during pregnancy?

Under normal circumstances, the absolute value of neutrophils in pregnant women will be slightly higher, which is a normal physiological change during pregnancy.

However, if the absolute value of neutrophils is significantly higher than the normal reference range, known as "neutrophilia", it needs to be taken seriously.

The common causes and solutions of neutrophilia during pregnancy are:


I. Bacterial infection

Due to decreased immunity during pregnancy, bacterial infections such as vaginitis and urinary tract infections are more likely to occur. Infection can cause inflammatory reactions and increased neutrophils.

Solution: Use safe antibiotics based on symptoms and lab results to treat infection. Pay attention to personal hygiene at the same time.

Solution details: Once obvious symptoms such as frequent urination, dysuria, vaginal itching occur, immediately perform urine routine, vaginal secretions and other tests.

If the infection is confirmed, select safe and effective antibiotics based on drug sensitivity test results, and treat for 7-10 days under doctor’s evaluation. Also pay attention to genital hygiene, avoid sexual contact, wear spandex underwear, etc.

The spouse of the pregnant woman should also pay attention to reproductive health.


II. Inflammatory reactions

Inflammation in the uterus or other parts can also increase neutrophils, such as complications of uterine fibroids, cholecystitis, etc.

Solution: Treat relevant inflammatory diseases accordingly, and neutrophils will return to normal as condition improves.

Solution details: For inflammatory reactions caused by uterine fibroids, consider undergoing myomectomy or uterine artery embolization after delivery.

For cholecystitis, pay close attention to symptoms at all times, once fever, jaundice and other symptoms occur, ultrasound or MRI is needed to confirm diagnosis.

Endure pain for a short time to protect fetus, or choose appropriate time for laparoscopic cholecystectomy.


III. Autoimmune diseases

Autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis can also lead to increased neutrophils.

Solution: Use medication rationally under doctor's guidance based on specific disease conditions to control condition.

Solution details: Lupus erythematosus requires reasonable use of corticosteroids or immunosuppressants under doctor’s guidance to control condition, while avoiding long-term high-dose medication.

Rheumatoid arthritis can experimentally use TNF inhibitors in early pregnancy, but should minimize types and dosage of medication used.

pobopobo- Hormone-level-changes

IV. Hormone level changes

Significant hormone changes during pregnancy may also affect white blood cells and neutrophils.

Solution: This is within the scope of physiological changes, it can be ensured within the normal range through regular monitoring.

Solution details: Monitor changes in neutrophil levels during pregnancy to see if they are within the normal physiological range through blood routine test every month or quarter. If abnormal, retest to rule out other causes.


V. Malnutrition

Lack of iron, vitamins and etc. can inhibit bone marrow hematopoietic function, leading to reduced neutrophils.

Solution: Supplement corresponding nutrients according to test results and improve diet.

Solution details: Detect indicators such as hemoglobin, serum iron, vitamin B12, judge type of nutritional deficiency, then make targeted supplements through dietary adjustments or oral supplements, monitor nutritional indicators monthly to reach normal range.

VI. Streptococcal infection

Streptococcal infections such as Staphylococcus aureus can occur during pregnancy, neutrophils are usually elevated.

Solution: Use safe antibiotics such as penicillin to treat streptococcal infection.

Solution details: See a doctor immediately if symptoms such as fever, uterine contraction occur. After diagnosis by bacterial culture, use penicillin for 4-7 days to completely eliminate streptococcus in the body. Repeat culture if necessary to prove pathogen elimination.

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VII. Gestational hypertension

Preeclampsia can lead to increased neutrophils.

Solution: Use medication to control blood pressure under doctor’s advice, and monitor pregnancy.

Solution details: Depending on severity of hypertension, reasonably select antihypertensive drugs such as methyldopa or magnesium sulfate under doctor’s guidance, hospitalize for pregnancy monitoring at the same time, closely observe changes in condition. Termination of pregnancy may be necessary if condition is critical.

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